Machine learning-based proteogenomic data modeling identifies circulating plasma biomarkers for early detection of lung cancer
Marcela A. Johnson, Shirley Nieves‐Rodriguez, Liping Hou, Bevan Emma Huang, Assieh Saadatpour, Abolfazl Doostparast Torshizi
This study uses machine learning to model proteogenomic data and identifies plasma biomarkers for early lung cancer detection, achieving AUCs of 0.78-0.88 in predicting diagnosis up to 9 years before symptoms.
Communications Medicine · Mar 13, 2026Peer-reviewedGenetic & Genomic Medicine