Author

Vladimir Denic

Harvard UniversityORCID 0000-0002-1982-7281Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Organism:yeast· 1

Frequent Co-Authors

Anna Huyen NgoiD· 1 shared Charlene ChaniD· 1 shared Houqing Yu· 1 shared Jason K. SelloiD· 1 shared Juliet A. LeeiD· 1 shared Philip AlabiiD· 1 shared Roarke A. KamberiD· 1 shared Victor Garcia-RuiziD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiochemistry

Anna Huyen NgoORCID

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2 papers

Recent·Most cited

Retrograde trafficking inhibitors allosterically trap Get3 to block tail-anchored protein biogenesis

Juliet A. Lee, Xilin Gu, Charlene Chan, Vida Storm Robertson, Victor Garcia-Ruiz, Yancheng E. Li, Anna Huyen Ngo, Philip Alabi, Vladimir Denic, Jason K. Sello, William Clemons

This study identifies Retro-1 and Retro-2 as inhibitors that trap Get3, blocking tail-anchored protein biogenesis by stabilizing a stalled complex.

bioRxiv · Jul 13, 2026 · PreprintBiochemistry

The peroxisomal exportomer directly inhibits phosphoactivation of the pexophagy receptor Atg36 to suppress pexophagy in yeast

Houqing Yu, Roarke A. Kamber, Vladimir Denic

The paper shows that the yeast exportomer complex inhibits Atg36 phosphorylation to prevent pexophagy, revealing a mechanism linking organelle biogenesis to autophagy regulation.

eLife · Mar 9, 2022Peer-reviewedMolecular Biology