Adam D. Silverman

Resolving Host-Episymbiont Interaction Dynamics through Continuous Cultivation

This study uses continuous cultivation to investigate episymbiont-host interactions, revealing distinct infection patterns and the role of host-binding factors in shaping these dynamics.

At-home, cell-free synthetic biology education modules for transcriptional regulation and environmental water quality monitoring

The paper develops four cell-free biosensing modules for synthetic biology education that enable students to explore transcriptional regulation and environmental monitoring without lab equipment.

Design and optimization of a cell-free atrazine biosensor

This paper designs a cell-free biosensor for atrazine detection using a metabolic pathway and a cyanuric acid biosensor, achieving faster and tunable detection compared to whole-cell sensors.

Point-of-Use Detection of Environmental Fluoride via a Cell-Free Riboswitch-Based Biosensor

This paper develops a cell-free biosensor for detecting fluoride in water using a riboswitch that produces fluorescent or colorimetric signals, demonstrating its effectiveness in both lab and field settings.

Design of a transcriptional biosensor for the portable, on-demand detection of cyanuric acid

This paper designs a portable biosensor for detecting cyanuric acid using a hybrid promoter system in E. coli, enabling rapid and on-demand detection with fluorescent and colorimetric reporters.

Deconstructing cell-free extract preparation for in vitro activation of transcriptional genetic circuitry

This study identifies protocol improvements for preparing cell-free extracts to enhance transcriptional activity of bacterial genetic circuits.