Blake J. Rasor

This paper develops a cell-free biosynthesis system for 1,2,4-butanetriol, achieving high productivity and yield at scale while reducing costs.

The paper develops four cell-free biosensing modules for synthetic biology education that enable students to explore transcriptional regulation and environmental monitoring without lab equipment.

This paper develops a dynamic kinetic model of cell-free metabolism to optimize butanol production, identifying aldehyde/alcohol dehydrogenase as a key bottleneck.

This paper develops a cell-free system for styrene biosynthesis, achieving titers 10 times higher than cellular methods by optimizing reaction conditions.

The paper introduces iPROBE, a platform for in vitro prototyping and rapid optimization of biosynthetic enzymes, demonstrating improved production of 3-hydroxybutyrate and n-butanol in microbial cell factories.

This paper develops modular plasmids for cell-free expression and genetic assembly in Clostridium to accelerate biosynthetic pathway testing.