Author

Ji‐Young Choi

Novartis (Switzerland)ORCID 0000-0002-2022-3741Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Alexandra Hinniger· 1 shared Alexandra Lavoisier· 1 shared Alexandra ProbstiD· 1 shared Alexandro LandshammeriD· 1 shared Beat NyfeleriD· 1 shared Benedikt GoretzkiiD· 1 shared Carole Manneville· 1 shared Catrin Swantje MülleriD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperSynthetic Biology

Alexandra Hinniger

Mutual co-authors in cluster

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2 papers

Recent·Most cited

FAM84B facilitates tau propagation via RYR3-mediated exocytosis in response to neuroinflammation

Gwangho Yoon, Hyeyeon Park, J. E. Park, Min Kyoung Kam, Jung-Hyun Kim, Eun‐Joo Kim, Sung-Hye Park, Hyunyoung Kim, Gail V.W. Johnson, Ji‐Young Choi, Young Ho Koh, Chulman Jo

This study identifies FAM84B as a novel protein facilitating tau propagation through RYR3-mediated exocytosis in response to neuroinflammation.

bioRxiv · Dec 29, 2025 · PreprintNeuroscience

Development of a p62 biodegrader for autophagy targeted degradation

Zacharias Thiel, David Marcellin, Carole Manneville, Benedikt Goretzki, Luca Egger, Rob Maher, Noémie Siccardi, Laura Torres, Alexandra Probst, Catrin Swantje Müller, Nathalie George, Markus Vogel, Sabine Sinterhauf, Alexandra Lavoisier, Ji‐Young Choi, , Beat Nyfeler

The paper develops a p62-based biodegrader that selectively degrades mitochondria via autophagy but not cytosolic proteins due to its effect on p62 self-oligomerization.

Nature Communications · Dec 3, 2025Peer-reviewedSynthetic Biology