Author

Rob Maher

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 1

Frequent Co-Authors

Benedikt GoretzkiiD· 2 shared Felix Freuler· 2 shared Alexandra Hinniger· 1 shared Alexandra Lavoisier· 1 shared Alexandra ProbstiD· 1 shared Alexandro LandshammeriD· 1 shared Amandine Rietsch· 1 shared Andreas Hofmann· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersSynthetic Biology

Benedikt GoretzkiORCID

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2 papers

Recent·Most cited

Development of a p62 biodegrader for autophagy targeted degradation

Zacharias Thiel, David Marcellin, Carole Manneville, Benedikt Goretzki, Luca Egger, Rob Maher, Noémie Siccardi, Laura Torres, Alexandra Probst, Catrin Swantje Müller, Nathalie George, Markus Vogel, Sabine Sinterhauf, Alexandra Lavoisier, Ji‐Young Choi, , Beat Nyfeler

The paper develops a p62-based biodegrader that selectively degrades mitochondria via autophagy but not cytosolic proteins due to its effect on p62 self-oligomerization.

Nature Communications · Dec 3, 2025Peer-reviewedSynthetic Biology

A novel HERC4-dependent glue degrader targeting STING

Merve Mutlu, Isabel Schmidt, Andrew I. Morrison, Benedikt Goretzki, Felix Freuler, Damien Begue, Nicolas Pythoud, Erik Ahrné, Sandra Kapps, Susan Roest, Débora Bonenfant, Delphine Jeanpierre, Thi-Thanh-Thao Tran, Rob Maher, Shaojian An, , Danilo Guerini

This paper identifies AK59 as a molecular glue degrader for STING, showing HERC4 is the key E3 ligase for its degradation and demonstrating efficacy against STING mutations.

bioRxiv · Feb 8, 2023 · PreprintMolecular Biology