Pratik Kamat

This study develops ovarian somatic organoids that maintain cellular diversity and reveal age-related changes in cellular composition and function.

This study identifies functional senescence subtypes in aging human dermal fibroblasts using single-cell morphology and machine learning, showing subtype-specific responses to senotherapies.

This study shows that substrate stiffness affects the development and strength of senescence features in fibroblasts, with mechanosensitive regulation of key biomarkers.

This paper quantifies geometric changes in D. radiodurans nucleoids under ionizing radiation using a new high-throughput method, revealing sub-population shifts and roles of nucleic acid binding proteins in nucleoid condensation.

The paper shows that different particulate matter mixtures cause distinct molecular and morphological changes in lung epithelial cells, with heavy metals causing more severe effects.