Hilleke E. Hulshoff Pol

This study links sulcal widening in schizophrenia to network hubs and genes involved in synaptic signaling and energy metabolism.

This paper meta-analyzes longitudinal diffusion MRI studies to show how white matter fractional anisotropy changes with age and identifies genetic influences on these changes.

The paper examines morphometric similarity networks in health and schizophrenia, finding reduced default mode network similarity in schizophrenia but minimal individual deviations over time.

The paper evaluates factors affecting brain-age prediction models using structural neuroimaging data from 35,683 individuals, finding optimal model performance with no site harmonization, age-binning, and a sample size of over 1,600.

This study compares neuronal phenotypes from monozygotic twins discordant for schizophrenia, finding differences in synaptic activity and neuronal maturation between affected and unaffected siblings.

The paper benchmarks and optimizes a normative modeling framework for brain morphometry across the lifespan using MFPR, showing excellent accuracy and stability.

The paper develops a deep learning model to automate fetal intracranial volume segmentation from 3D ultrasound and finds sex differences in ICV and growth.

This study examines heritability of urinary metabolites in children, finding substantial genetic contributions across amines, organic acids, and steroids.

The paper examines longitudinal allometric scaling of sulcal morphology in health and schizophrenia, finding steeper age-related declines in SZ compared to healthy individuals.

The paper examines age-related variations in cortical thickness across different life stages using gene expression data from a large neuroimaging dataset.

The paper examines sex differences in lifespan trajectories and variability of human sulcal and gyral morphology using longitudinal neuroimaging data.

The paper analyzes cortical thickness trajectories in 17,075 individuals to show peak thickness in childhood, steep decline in early adulthood, and slower decline later, with notable exceptions and significant inter-individual variability.

This study identifies shared genetic loci between ADHD, aggressive behaviors, and antisocial behaviors using GWAS and gene-based analyses.

The paper analyzes sex differences in brain structure variability across the lifespan using a large dataset, finding greater male variability in subcortical volumes, cortical surface area, and thickness in most regions.

The paper identifies a subgroup of schizophrenia patients with extreme cognitive deficits by analyzing sulcal width dissimilarity using the PBSI-SW metric.

This study analyzes subcortical volume changes across the lifespan using MRI data from 18,605 individuals, finding age-related declines in some structures and increases in others.

This study reports longitudinal changes in intracranial volume (ICV) from early adulthood to the sixth decade, finding increases until the fourth decade followed by decreases, with cross-sectional results showing larger changes.

This study identifies DNA methylation changes in blood samples from psychosis patients, including treatment-resistant schizophrenia, and links them to biological age, smoking, and cellular composition.

The paper reports epigenome-wide meta-analyses of blood DNA methylation with subcortical brain volumes, identifying significant associations with hippocampal volume and potential biological mechanisms.