NeurosciencebioRxivPreprint
The c-Src inhibitor eCF506 diminishes opioid tolerance creating bias against β-arrestin2 recruitment
Samuel Singleton, Fraser Nunn, Erika Lace…·Tim G. Hales
The paper tests eCF506, a c-Src inhibitor, showing it reduces opioid tolerance by decreasing β-arrestin2 recruitment without affecting cAMP inhibition.
DOI 10.1101/2025.07.01.662507