Asier Unciti‐Broceta

This study identifies Molidustat's anti-tumor effect in APC-mutant colorectal cancer through co-inhibition of GSTP1 and PHD2, revealing a synthetic lethal interaction.

This study identifies three compounds targeting glioblastoma stem cells using machine learning and high-throughput screening of patient-derived models.

The paper tests eCF506, a c-Src inhibitor, showing it reduces opioid tolerance by decreasing β-arrestin2 recruitment without affecting cAMP inhibition.

This study shows that collagen scar formation during bile duct regeneration alters biomechanical properties, activating integrin-SRC/FAK signaling to drive ductular regeneration through a leading-tip of integrin-2-high cells.