Author

Toril Holien

Norwegian University of Science and TechnologyORCID 0000-0002-2051-5824Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:biophysical modeling· 1 Assay:CRISPR screen· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

Ingrid Quist-LøkkeniD· 2 shared Ahmed Bulldan· 1 shared Alexander LoeweriD· 1 shared Barbara van LooniD· 1 shared Christian MeynersiD· 1 shared Clara Andersson-RuschiD· 1 shared Felix HauschiD· 1 shared Ingo Volker HartungiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Ingrid Quist-LøkkenORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 9, 2025

Whole genome CRISPR knockout screen reveals ID3 as a key regulator of myeloma cell survival via TCF3 and c-MYC

Clara Andersson-Rusch, Md. Abu Hanif, Ingrid Quist-Løkken…·Toril Holien

DOI 10.1101/2025.09.09.675036

humanCRISPR screen

𝕏 PostBluesky

BiochemistrybioRxivPreprintMay 16, 2025

Heterobifunctional Protein Binders Enable Cell Type-Specific Killing Through In-cell Enrichment

Ahmed Bulldan, Min Jing Zheng, Christian Meyners…·Felix Hausch

This study develops heterobifunctional protein binders that selectively kill specific cell types by leveraging the abundance of FKBP12, demonstrating enhanced efficacy through cellular enrichment.

2 citations

humanproteomics

𝕏 PostBluesky