James T. Kadonaga

Different modes of engagement with the nucleosome acidic patch yield distinct functional outcomes

The paper shows that different binding modes to the nucleosome acidic patch lead to distinct cellular outcomes, with overexpression of Dot5 and camelid antibodies causing growth, DNA repair, and heterochromatin defects.

The HMGN Proteins Are Transcriptional Regulatory Factors in Humans

This study investigates the genome-wide transcriptional activities of HMGN proteins in human cells, revealing their role in activating gene expression at promoters and enhancers.

Machine Learning Analysis of the Human Initiator Region Reveals Key Features of Different Types of Core Promoters

The paper develops machine learning models to analyze the human initiator region, identifying key features of core promoters and their functional relationships.

Structural basis of nucleosome recognition by the conserved Dsup and HMGN nucleosome-binding motif

This study determines the structure of the Dsup and HMGN nucleosome-binding motif using cryo-EM, revealing their binding to the nucleosome acidic patch.