Qi Dai

Drosophila Hamlet mediates epithelial tissue assembly of the reproductive system

This study identifies Hamlet as a key regulator of epithelial tissue fusion in Drosophila reproductive system, revealing its role in gene regulation and tissue connectivity.

PRDM16 functions as a co-repressor in the BMP pathway to suppress neural stem cell proliferation

This study identifies PRDM16 as a co-repressor in the BMP pathway that suppresses neural stem cell proliferation by regulating SMAD complex genomic distribution and gene expression.

Continual inactivation of genes involved in stem cell functional identity stabilizes progenitor commitment

The paper identifies Tailless as a master regulator maintaining neuroblast identity and shows its inactivation stabilizes intermediate progenitor commitment during neurogenesis.

BEN-solo factors partition active chromatin to ensure proper gene activation in Drosophila

This study investigates the in vivo functions of BEN-solo proteins in Drosophila embryos, showing they act as insulators to partition active chromatin and regulate gene activation.

PRDM16 establishes lineage-specific transcriptional program to promote temporal progression of neural progenitors in the mouse neocortex

This study shows PRDM16 promotes temporal progression of neural progenitors in the mouse neocortex by regulating gene expression and chromatin accessibility.