Author

Katherine S. Pawelczak

NĒRx BioSciences (United States)ORCID 0000-0002-2099-2858Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:CUT&Tag· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Hilary D. Hinshaw· 1 shared John J. TurchiiD· 1 shared Joy Garrett· 1 shared Jun WaniD· 1 shared Karen E. PollokiD· 1 shared Matthew R. JordaniD· 1 shared Pamela S. VanderVere-Carozza· 1 shared Sheng LiuiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

Hilary D. Hinshaw

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1 paper

Recent·Most cited

Chemical inhibition of RPA gap protection sensitizes BRCA1-deficient cancers to PARP inhibition

Pamela S. VanderVere-Carozza, Matthew R. Jordan, Joy Garrett, Karen E. Pollok, Hilary D. Hinshaw, Xierzhatijiang Sulaiman, Sheng Liu, Jun Wan, Katherine S. Pawelczak, John J. Turchi

This study shows that inhibiting RPA gap protection enhances PARP inhibitor efficacy in BRCA1-deficient cancers by increasing genomic instability and reducing tumor growth.

bioRxiv · Apr 9, 2025 · PreprintCancer Biology