Ozcan Gazioglu

Rgg144/SHP144 - controlled Streptolancidin D mediates intra-species competition in Streptococcus pneumoniae with cumulative effect from other bacteriocins and fratricide

This paper identifies and characterizes streptolancidin D, a bacteriocin in Streptococcus pneumoniae regulated by Rgg144/SHP144, which enhances intra-species competition and is effective against diverse isolates.

Large scale antibiotic-phage synergy studies reveal key combinations for urinary tract infection and urosepsis treatments

This study screens phage-antibiotic combinations in clinical isolates to identify synergistic interactions for treating resistant infections.

Coexistence of two divergent TprA/PhrA cell-cell communication systems in Streptococcus mitis coordinate bacteriocin production, competence, oxidative stress responses, and interspecies competition with S. pneumoniae

Network rewiring of a pneumococcal communication system promotes stress adaptation in a globally successful lineage

The paper identifies a non-functional variant of a bacterial communication system that rewires gene regulation to enhance stress adaptation and colonization in a globally successful Streptococcus pneumoniae lineage.

Simple Sequence Repeats Mediate Phase Variation of the Mucoid Phenotype in Hypervirulent Klebsiella pneumoniae

This study identifies simple sequence repeats in rmpA and rmpD/rmpC genes that mediate phase variation of the mucoid phenotype in hypervirulent Klebsiella pneumoniae, enabling adaptation to different infection niches.