Cell free extrachromosomal circular DNA is common in human urine
Wei Lv, Xiaoguang Pan, Peng Han, Ziyu Wang, Hao Yuan, Weijia Feng, Qingqing Wang, Kunli Qu, Zhe Xu, Yi Li, Tianyu Zheng, Ling Lin, Chengxun Liu, Xuemei Liu, Hanbo Li, , Yonglun Luo
This study identifies and characterizes over one million urinary cell free eccDNAs in healthy adults, revealing their genomic distribution, sequence features, and potential role of direct repeats in their biogenesis.
bioRxiv · Dec 2, 2021 · PreprintGenomics