Author

Hao Yuan

Chinese Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Bin XiaoiD· 1 shared Birgitte RegenbergiD· 1 shared Chengxun LiuiD· 1 shared Fangze Qian· 1 shared Gao WentaoiD· 1 shared Gongchao JingiD· 1 shared Han LiangiD· 1 shared Hanbo LiiD· 1 shared

Activity by Year

2021-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperCancer Biology

Bin XiaoORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Genomic splice-donor disruption rescues systemic disease in progeria

Wei Zhu Jin, Jingchun Ma, Hao Yuan, Yu Zou, Zixuan Zhang, Jinhang Zuo, Sheung Kin Ken Wong, Tuo Li, Xiaomei Lu, Zhongjun Zhou

This paper shows that disrupting a faulty splice donor site in progeria reduces toxic protein levels and extends lifespan in mice.

bioRxiv · Sep 18, 2026 · PreprintCell Biology

Co-evolution of Oncogenic KRAS Signaling and LILRBhigh Macrophages Drives Pancreatic Cancer Recurrence

Jianzhen Lin, Zhenzhen Xun, Fangze Qian, Zhigao Chen, Weikang Hu, W. Liu, Yang Wu, Hao Yuan, Lingdi Yin, Yuxing Wang, Xiao Huang, Yujia Dang, Bin Xiao, Junli Wu, Gao Wentao, , Han Liang

This study identifies a co-evolved tumor-immune interaction involving KRAS signaling and LILRBhigh macrophages that drives PDAC recurrence and presents a therapeutic strategy targeting this axis.

bioRxiv · Mar 7, 2026 · PreprintCancer Biology

RamEx: An R package for high-throughput microbial ramanome analyses with accurate quality assessment

Yanmei Zhang, Gongchao Jing, Rongze Chen, Yanhai Gong, Yuandong Li, Yongshun Wang, Xixian Wang, Jia Zhang, Yuli Mao, Yi He, Xiaoshan Zheng, Mingchao Wang, Hao Yuan, Jian Xu, Luyang Sun

RamEx is an R package for high-throughput microbial ramanome analysis with quality assessment and classification, achieving high accuracy in anomaly detection and phenotyping.

Microbiome · Feb 10, 2026Peer-reviewedBioinformatics

Cell free extrachromosomal circular DNA is common in human urine

Wei Lv, Xiaoguang Pan, Peng Han, Ziyu Wang, Hao Yuan, Weijia Feng, Qingqing Wang, Kunli Qu, Zhe Xu, Yi Li, Tianyu Zheng, Ling Lin, Chengxun Liu, Xuemei Liu, Hanbo Li, , Yonglun Luo

This study identifies and characterizes over one million urinary cell free eccDNAs in healthy adults, revealing their genomic distribution, sequence features, and potential role of direct repeats in their biogenesis.

bioRxiv · Dec 2, 2021 · PreprintGenomics