Paul C. J. Armstrong

The paper investigates how ZEB85 activates TrkB by identifying a sulfotyrosine motif essential for agonist activation, while BDNF uses a different binding site.

This study shows that platelet depletion in schistosomiasis leads to severe bleeding and reduced survival, while platelets do not directly drive macrophage activation in type 2 inflammation.

This study shows that platelet extracellular vesicles containing mitochondria are internalized by neutrophils, altering their activation, adhesion, migration, and phagocytic capacity.

This paper uses multi-parameter flow cytometry and machine learning to characterize platelet sub-populations and their responses to agonists, achieving high accuracy in distinguishing platelet age and activation states.