Author

Jordi L. Tremoleda

Queen Mary University of LondonORCID 0000-0002-8846-9043Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Jordi Lopez-Tremoleda1 paper · University of London

Biology Disciplines

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Cell Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Organism:non-human primate· 1 Approach:statistical model· 1

Frequent Co-Authors

Aarti SinghiD· 1 shared Angela M. Maldonado· 1 shared Aylin Olkun· 1 shared Danilo FaccendaiD· 1 shared Dong Xia· 1 shared Eleanor J. Smith· 1 shared Gopinath LakshmananiD· 1 shared Harriet E. AllaniD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCell Biology

Aarti SinghORCID

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Author profile →

3 papers

Recent·Most cited

Mitochondria drive microglial NRLP3 inflammasome activation via TSPO

Aarti Singh, Manuel Rigon, Tong Guo, Danilo Faccenda, Gopinath Lakshmanan, Dong Xia, Marta Gramaça Caldeira, Jordi Lopez-Tremoleda, Z. Falah Hassan Al-Khateeb, Rosella Abeti, Paola Giunti, Michelangelo Campanella

This study shows TSPO on mitochondria promotes microglial inflammasome activation by stabilizing NLR proteins, inhibiting mitophagy, and enhancing pro-inflammatory gene expression, leading to excitotoxicity.

Pharmacological Research · Feb 19, 2026Peer-reviewedCell Biology

Megakaryocyte activation and mobilization from the bone marrow in response to trauma and hemorrhagic shock in mice

Isabelle C. Becker, Eleanor J. Smith, Nicola Dark, Jordi L. Tremoleda, Harriet E. Allan, Paul Vulliamy

This study shows trauma and hemorrhagic shock rapidly alter megakaryocyte activity and mobilization in mice within one hour.

bioRxiv · Feb 11, 2026 · PreprintCell Biology

Rejection in early life is associated with high and long-lasting stress and higher incidence of infections in owl monkeys

Mahdiyah Osman, Aylin Olkun, Angela M. Maldonado, Jordi L. Tremoleda, Nofre Sanchez‐Perea, Ursula M. Paredes

The paper examines the long-term effects of maternal rejection in owl monkeys, finding higher stress levels and infection rates in rejected infants compared to controls.

bioRxiv · Oct 17, 2020 · PreprintNeuroscience