Robust Hi-C chromatin loop maps in human neurogenesis and brain tissues at high-resolution
Leina Lu, Xiaoxiao Liu, Wei‐Kai Huang, Paola Giusti‐Rodríguez, Jian Cui, Shanshan Zhang, Wanying Xu, Zhexing Wen, Shufeng Ma, Jonathan D. Rosen, Zheng Quan Xu, Cynthia F. Bartels, Riki Kawaguchi, Ming Hu, Peter C. Scacheri, , Fulai Jin
The paper develops an improved Hi-C protocol and bias-correction pipeline to map chromatin loops in human neurogenesis and brain tissues, showing their role in neural differentiation and GWAS gene identification.
bioRxiv · Aug 22, 2019 · PreprintGenomics