Yiming Zhou

This study identifies a UVB-induced MIF-p38 feedback loop in lupus keratinocytes that drives cutaneous lupus erythematosus and shows a microneedle patch targeting MIF can alleviate skin lesions.

The paper identifies obesity-related TREM2high macrophages in diabetic mouse and human kidney through single-cell transcriptomics and cross-species comparison.

The paper uses single-cell RNA-Seq to assess kidney organoid reproducibility across iPSC lines and shows transplantation reduces off-target cells.

The paper develops a cell lysate microarray (CLICK) to identify upstream regulators of histone marks using yeast knockout and temperature-sensitive mutant strains, revealing new regulators and enzymes involved in histone acylation.