Sheng‐ce Tao

This study identifies EccB5 as a key Mtb effector that drives pyroptosis and enhances virulence by interacting with GSDMD and caspase-1.

CHAIR provides an antigen-resolved immune resource for healthy adult aging by integrating PhIP-seq, clinical data, and immune phenotyping across multiple age groups.

APPLE-MS improves protein-protein interaction detection by combining proximity labeling with high-specificity enrichment, revealing novel interactions and dynamics in mitochondrial and membrane-associated contexts.

This study shows c-di-GMP inhibits rRNA methylation by binding to RlmI, modulates ribosome assembly, and promotes antibiotic tolerance in E. coli.

The paper introduces SPIDER, a method using pupylation and streptavidin-biotin to identify protein-biomolecule interactions, demonstrating its application in various biological contexts.

This study reports the structure of SARS-CoV-2 RdRp with and without Remdesivir, showing how the drug inhibits viral RNA replication by terminating chain elongation.

The paper develops a cell lysate microarray (CLICK) to identify upstream regulators of histone marks using yeast knockout and temperature-sensitive mutant strains, revealing new regulators and enzymes involved in histone acylation.