Chipeng Guo

This study evaluates the antibody evasion and receptor binding of SARS-CoV-2 variants PQ.16.1.1 and RK.1, finding reduced ACE2 engagement but increased immune evasion.

This study identifies Piezo1 as a mechanoreceptor in kidney medulla macrophages that enables them to clear sedimentary particles and prevent kidney stones.

This paper develops a multivalent NET-neutralizer that reduces inflammation in severe sepsis by targeting DNA-histone chromatin complexes while maintaining antibacterial activity.

Steller improves clonal detection sensitivity in spatial transcriptomics and reveals region-specific spatial clonal architectures in the developing mouse forebrain.

This study identifies a UVB-induced MIF-p38 feedback loop in lupus keratinocytes that drives cutaneous lupus erythematosus and shows a microneedle patch targeting MIF can alleviate skin lesions.