Author

Christian Pasquali

OM Pharma (Switzerland)ORCID 0000-0002-2117-8487Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Christian Pasquali2 papers

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Organism:human· 1

Frequent Co-Authors

Allison M. BurnsiD· 1 shared Edouard Baulier· 1 shared Gauri PadutholiD· 1 shared John D. McKinneyiD· 1 shared Kathrin TomasekiD· 1 shared Kristina SkurvydaiteiD· 1 shared Léa SchlunkeiD· 1 shared Mario RomaniiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

Allison M. BurnsORCID

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2 papers

Recent·Most cited

Lysosomal activation in bladder epithelium enhances intracellular antibiotic clearance of uropathogenic Escherichia coli

Kathrin Tomasek, Kristina Skurvydaite, Gauri Paduthol, Allison M. Burns, Léa Schlunke, Valentin Borgeat, Christian Pasquali, Mario Romani, John D. McKinney

This study shows that OM-89 enhances lysosomal activity in bladder epithelial cells, improving antibiotic efficacy against UPEC and reducing bacterial regrowth.

bioRxiv · Oct 22, 2025 · PreprintMicrobiology

Oral OM-89 in combination with antibiotics prevents recurrent infection in a mouse model of urinary tract infection

Tracy Canton, Méline Durand, Edouard Baulier, Christian Pasquali, Ruxandra Câlin, Molly A. Ingersoll, Matthieu Rousseau

This study shows that OM-89 combined with antibiotics reduces recurrent UTI in mice, without affecting adaptive immunity.

bioRxiv · Apr 4, 2025 · PreprintImmunology