John D. McKinney

The paper develops a human urothelial organoid model to study urine-urothelium interactions in UTI resilience and UPEC recurrence, finding that high-solute urine weakens tissue and promotes CWD UPEC formation.

This study shows that OM-89 enhances lysosomal activity in bladder epithelial cells, improving antibiotic efficacy against UPEC and reducing bacterial regrowth.

This paper introduces a hermetically sealed AFM sample chamber for safe, high-resolution time-lapse imaging of pathogenic microorganisms in vitro.