Author

Jumana M. Yousef

The University of MelbourneORCID 0000-0002-2364-6299Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:proteomics· 3 Approach:biophysical modeling· 2 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Laura F. DagleyiD· 4 shared Toby A. DiteiD· 2 shared Alexandra D. GurzauiD· 1 shared Alexandra L. GarnhamiD· 1 shared Andrew J. KuehiD· 1 shared Andrew P. LeisiD· 1 shared Anna Gabrielyan· 1 shared Anthony R. MeansiD· 1 shared

Activity by Year

2024-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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4 shared papersCell Biology

Laura F. DagleyORCID

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Author profile →

4 papers

Recent·Most cited

ARAP2 regulates responses to interferon-gamma by restricting SOCS1

Narelle Keating, Karen Doggett, Grace M. Bidgood, Lizeth G. Meza Guzman, Laura F. Dagley, Kunlun Li, Bailey E. Williams, Anna Gabrielyan, Carolina Alvarado, Benjamin J. Broomfield, Brigette C. Duckworth, Colin Hockings, Jumana M. Yousef, Evelyn Leong, Rhiannon Morris, , Sandra E. Nicholson

This study identifies ARAP2 as a regulator of IFN-gamma signaling by modulating SOCS1 function through a phosphorylation-dependent interaction.

Cell Reports · Dec 1, 2025Peer-reviewedCell Biology

MORC2 phosphorylation fine tunes its DNA compaction activity

Winnie Tan, J.-G. Park, Hariprasad Venugopal, Jieqiong Lou, Prabavi Shayana Dias, Pedro L. Baldoni, Kyoung-Wook Moon, Toby A. Dite, Christine R. Keenan, Alexandra D. Gurzau, Joonyoung Lee, Timothy M. Johanson, Andrew P. Leis, Jumana M. Yousef, Vineet Vaibhav, , Shabih Shakeel

This study characterizes MORC2 phosphorylation's role in DNA compaction and chromatin remodelling, showing it regulates ATP hydrolysis and DNA binding.

Nature Communications · Jul 1, 2025Peer-reviewedMolecular Biology

PSKH1 kinase activity is differentially modulated via allosteric binding of Ca2+ sensor proteins

Christopher R. Horne, Toby A. Dite, Samuel N. Young, Lucy J. Mather, Laura F. Dagley, Jared Lee Johnson, Tomer M. Yaron, Emily M. Huntsman, Leonard A. Daly, Dominic P. Byrne, Antonia L. Cadell, Boaz H. Ng, Jumana M. Yousef, Dylan H. Multari, Lianju Shen, , James M. Murphy

The paper identifies allosteric regulation of PSKH1 kinase activity by Ca2+ sensor proteins, showing both activation and suppression by different sensors.

Proceedings of the National Academy of Sciences · Feb 18, 2025Peer-reviewedBiochemistry

Scanning ultrasound-mediated memory and functional improvements do not require amyloid-β reduction

Gerhard Leinenga, Xuan Vinh To, Liviu‐Gabriel Bodea, Jumana M. Yousef, Gina L. Richter-Stretton, Tishila Palliyaguru, Antony Chicoteau, Laura F. Dagley, Fatima Ali Nasrallah, Jürgen Götz

The paper shows that ultrasound treatment improves memory in AD mice without reducing amyloid-β, with higher frequency (1 MHz) being more effective than lower frequencies.

Molecular Psychiatry · Mar 18, 2024Peer-reviewedNeuroscience