Author

Valeria Impedovo

The University of Texas at AustinORCID 0000-0002-2166-4303Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1 Assay:proteomics· 1

Frequent Co-Authors

Natalia BaraniD· 2 shared Stefano TizianiiD· 2 shared Abhishek MaitiiD· 1 shared Agnieszka E. GorskaiD· 1 shared Anand Kamal SinghiD· 1 shared Andrea D. BedoyiD· 1 shared Andrew J. MonteithiD· 1 shared Anna SkwarskaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Natalia BaranORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJul 13, 2026

Specific F1 ATP synthase inhibition delivers transient mitochondrial stress for selective targeting of acute myeloid leukemia

Matthew T. Villaume, Haley Elizabeth Ramsey, Valeria Impedovo…·Michael Robert Savona

This study shows that inhibiting F1 ATP synthase with EB2023 causes transient mitochondrial stress in AML cells, enabling effective treatment without harming healthy tissues.

DOI 10.64898/2026.07.10.737821

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintApr 24, 2025

Dual MYC and GSPT1 Protein Degrader for MYC-Driven Cancers

Yuki Nishida, Valeria Impedovo, Edward Ayoub…·Michael Andreeff

This paper identifies a novel MYC-GSPT1 feedback loop and reports a dual degrader, GT19630, that effectively targets MYC-driven cancers with anti-proliferative and apoptotic effects.

DOI 10.1101/2025.04.24.650490

humanproteomics

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