Stephen G. Waxman

The paper investigates how combinations of Nav1.7 and Nav1.8 channels affect nociceptor excitability, showing that their synergistic effects vary across neuronal subtypes.

APpar automates action potential parameter extraction in neuronal electrophysiology, improving reproducibility through threshold validation and standardized measurements.

This study identifies Nav1.5 in TrkB+ sensory neurons as a driver of paclitaxel-induced mechanical pain hypersensitivity in mice, with potential translational relevance to humans.

The paper identifies human-specific transcriptomic and regulatory features in the cerebellum, including ZP2's role in synapse development and regulation.

This paper identifies cell-type-specific genetic variants associated with chronic pain using GWAS and scRNA-seq data from brain and dorsal root ganglia tissues.

This study develops a therapeutic protein, UbiquiNaV, that reduces NaV1.8 channel expression in sensory neurons, alleviating pain in preclinical models.

This paper introduces VR-SASE, a VR platform for dendritic spine analysis that outperforms existing tools and aligns with FAIR data principles.