Author

Nicolas Gautron

Université de ToursORCID 0000-0002-2184-7302Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:plant (other)· 1 Assay:whole-genome sequencing· 1 Organism:yeast· 1

Frequent Co-Authors

Vincent CourdavaultiD· 3 shared Audrey OudiniD· 2 shared Benoit St‐PierreiD· 2 shared Caroline M. C. Birer-WilliamsiD· 2 shared Enzo LeziniD· 2 shared Mehdi A. BeniddiriD· 2 shared Mickaël DurandiD· 2 shared Nathalie Giglioli‐Guivarc’hiD· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersPlant Biology

Vincent CourdavaultORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

FASTOP - Fast editing toolkit for top expression sites in yeast

Madhushruti Borah, Nicolas Gautron, Vincent Courdavault, Gita Naseri

The paper introduces FASTOP, a genome-editing toolkit for yeast that enables rapid and reliable modification of transcriptionally active loci to construct multi-enzymatic pathways, achieving high production of naringenin.

bioRxiv · May 8, 2026 · PreprintSynthetic Biology

Geissoschizine scaffolding enzymes shape monoterpene indole alkaloid biosynthesis

David Brelu-Brelu, Enzo Lezin, Emma Parker Miller, Duchesse‐Lacours Zamar, Mickaël Durand, Sitakanta Pattanaik, Barunava Patra, Nicolas Gautron, Caroline M. C. Birer-Williams, Thomas Perrot, Arnaud Lanoue, Audrey Oudin, Pierre Le Pogam, Mehdi A. Beniddir, Nathalie Giglioli‐Guivarc’h, , Vincent Courdavault

The paper identifies MDR proteins as regulators of geissoschizine biosynthesis, enhancing activity and diversifying stereochemical outputs through ternary complex formation with GS and SGD.

bioRxiv · May 3, 2026 · PreprintPlant Biology

Genome-based discovery of pachysiphine synthases in Tabernaemontana elegans

Enzo Lezin, Mickaël Durand, Caroline M. C. Birer-Williams, Adriana González Vázquez, Thomas Perrot, Nicolas Gautron, Julien Pétrignet, Clément Cuello, Hans J. Jansen, Florent Magot, Sarah Szwarc, Pierre Le Pogam, Mehdi A. Beniddir, Konstantinos Koudounas, Audrey Oudin, , Vincent Courdavault

This paper identifies and characterizes pachysiphine synthase genes in Tabernaemontana elegans using genome sequencing and computational analysis, enabling engineered yeast production of MIAs.

The Plant Journal · Oct 20, 2024Peer-reviewedPlant Biology