Author

Thomas Perrot

Université de ToursORCID 0000-0002-5592-7941Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:plant (other)· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Audrey OudiniD· 3 shared Benoit St‐PierreiD· 3 shared Caroline M. C. Birer-WilliamsiD· 3 shared Enzo LeziniD· 3 shared Mickaël DurandiD· 3 shared Nicolas PaponiD· 3 shared Sébastien BesseauiD· 3 shared Vincent CourdavaultiD· 3 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersPlant Biology

Audrey OudinORCID

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Author profile →

3 papers

Recent·Most cited

Geissoschizine scaffolding enzymes shape monoterpene indole alkaloid biosynthesis

David Brelu-Brelu, Enzo Lezin, Emma Parker Miller, Duchesse‐Lacours Zamar, Mickaël Durand, Sitakanta Pattanaik, Barunava Patra, Nicolas Gautron, Caroline M. C. Birer-Williams, Thomas Perrot, Arnaud Lanoue, Audrey Oudin, Pierre Le Pogam, Mehdi A. Beniddir, Nathalie Giglioli‐Guivarc’h, , Vincent Courdavault

The paper identifies MDR proteins as regulators of geissoschizine biosynthesis, enhancing activity and diversifying stereochemical outputs through ternary complex formation with GS and SGD.

bioRxiv · May 3, 2026 · PreprintPlant Biology

Evolution of CYP71D as a driving force of the diversification of monoterpene indole alkaloid biosynthesis

Sébastien Besseau, Mickaël Durand, Duchesse‐Lacours Zamar, Enzo Lezin, Louis‐Valentin Méteignier, Caroline M. C. Birer-Williams, Christelle Dutilleul, Thomas Perrot, Arnaud Lanoue, Audrey Oudin, Nicolas Papon, Georges Massiot, Chao Sun, Benoit St‐Pierre, Vincent Courdavault

This study investigates the evolutionary diversification of CYP71D enzymes in Gentianales, showing how gene duplication and neofunctionalization expanded MIA chemical diversity.

Plant Communications · May 19, 2025Peer-reviewedBiochemistry

Genome-based discovery of pachysiphine synthases in Tabernaemontana elegans

Enzo Lezin, Mickaël Durand, Caroline M. C. Birer-Williams, Adriana González Vázquez, Thomas Perrot, Nicolas Gautron, Julien Pétrignet, Clément Cuello, Hans J. Jansen, Florent Magot, Sarah Szwarc, Pierre Le Pogam, Mehdi A. Beniddir, Konstantinos Koudounas, Audrey Oudin, , Vincent Courdavault

This paper identifies and characterizes pachysiphine synthase genes in Tabernaemontana elegans using genome sequencing and computational analysis, enabling engineered yeast production of MIAs.

The Plant Journal · Oct 20, 2024Peer-reviewedPlant Biology