Vincent Courdavault

Multiple Shifts from Peptide-Based to Metabolite-Based Venoms in Ants

This paper identifies seven independent transitions from peptide-based to metabolite-based venoms in ants, linked to ecological and morphological changes.

FASTOP - Fast editing toolkit for top expression sites in yeast

The paper introduces FASTOP, a genome-editing toolkit for yeast that enables rapid and reliable modification of transcriptionally active loci to construct multi-enzymatic pathways, achieving high production of naringenin.

Geissoschizine scaffolding enzymes shape monoterpene indole alkaloid biosynthesis

The paper identifies MDR proteins as regulators of geissoschizine biosynthesis, enhancing activity and diversifying stereochemical outputs through ternary complex formation with GS and SGD.

Evolution of CYP71D as a driving force of the diversification of monoterpene indole alkaloid biosynthesis

This study investigates the evolutionary diversification of CYP71D enzymes in Gentianales, showing how gene duplication and neofunctionalization expanded MIA chemical diversity.

Genome-based discovery of pachysiphine synthases in Tabernaemontana elegans

This paper identifies and characterizes pachysiphine synthase genes in Tabernaemontana elegans using genome sequencing and computational analysis, enabling engineered yeast production of MIAs.

Ranking genome-wide correlation measurements improves microarray and RNA-seq based global and targeted co-expression networks

The paper evaluates correlation methods for constructing co-expression networks using microarray and RNA-seq data in Arabidopsis thaliana, finding that PCC with HRR performs best for global networks and pathway-level correlations.