Christine Mau

Single-cell transcriptomics of enriched rare neural lineages of Tribolium castaneum

The paper develops workflows for targeted single-cell and single-nucleus RNA sequencing of rare neural populations in Tribolium castaneum using reporter and antibody-based enrichment strategies.

Enhancer RNA Transcription Near Segmentation Gene Enhancers Can Be Analyzed In Situ Using FISH

This paper introduces an experimental assay to analyze eRNA transcription in Drosophila embryos using FISH and imaging, revealing eRNA dynamics and insulator effects.

High-multiplexity imaging reveals that temporal-to-spatial patterning of embryonic structures can involve active transformation of temporal information rather than direct mapping

The paper uses high-multiplexity imaging to show that spatial patterns in Tribolium embryos are actively reshaped during gene propagation rather than directly mapped from temporal gene expression.

Gene network switching provides a mechanistic basis for time-to-space translation in insect embryonic patterning

The paper shows that morphogen-driven rewiring of gene regulatory networks converts temporal gene activation sequences into stable spatial patterns in insect embryos.

How enhancers regulate wavelike gene expression patterns: Novel enhancer prediction and live reporter systems identify an enhancer associated with the arrest of pair-rule waves in the short-germ beetle Tribolium

The paper identifies enhancers in Tribolium that regulate wavelike gene expression patterns by distinguishing dynamic and static enhancers.

Speeding up anterior-posterior patterning of insects by differential initialization of the gap gene cascade

The paper explains how Drosophila evolved a faster, simultaneous mode of anterior-posterior patterning by switching from uniform to gradient-mediated gap gene initialization.