Heike Rudolf

Gene network switching provides a mechanistic basis for time-to-space translation in insect embryonic patterning

The paper shows that morphogen-driven rewiring of gene regulatory networks converts temporal gene activation sequences into stable spatial patterns in insect embryos.

How enhancers regulate wavelike gene expression patterns: Novel enhancer prediction and live reporter systems identify an enhancer associated with the arrest of pair-rule waves in the short-germ beetle Tribolium

The paper identifies enhancers in Tribolium that regulate wavelike gene expression patterns by distinguishing dynamic and static enhancers.

Speeding up anterior-posterior patterning of insects by differential initialization of the gap gene cascade

The paper explains how Drosophila evolved a faster, simultaneous mode of anterior-posterior patterning by switching from uniform to gradient-mediated gap gene initialization.

A re-inducible gap gene cascade patterns the anterior-posterior axis of insects in a threshold-free fashion

The paper shows that gap gene expression in Tribolium castaneum is controlled by a threshold-free Speed Regulation mechanism rather than a threshold-based French Flag model.

Enhancer identification and activity evaluation in the red flour beetle, Tribolium castaneum

The paper identifies and evaluates enhancer activity in Tribolium castaneum using chromatin profiling and a cross-species reporter assay system.