Alexis Villars

Interfacial tension and growth both contribute to mechanical cell competition

This study identifies two modes of cell compaction during mechanical cell competition: growth-driven and interfacial tension-driven, using Drosophila pupal notum.

Integration of past caspase activity biases cell elimination in vivo

The paper shows that past sublethal caspase activity influences cell elimination decisions in Drosophila, revealing a new layer of apoptosis regulation.

Developmental delay ensures global tissue size robustness upon local induction of apoptosis

The study shows that tissue size remains robust during mild apoptosis induction through a global growth delay rather than local proliferation, using Drosophila wing discs.

DeXtrusion: Automatic recognition of epithelial cell extrusion through machine learning in vivo

DeXtrusion automatically detects cell extrusion and death in epithelial tissues using machine learning, improving efficiency over manual methods.

Robustness of epithelial sealing is an emerging property of local ERK feedbacks driven by cell elimination

The paper shows that local ERK feedbacks prevent concomitant cell elimination in epithelia, maintaining sealing during high cell death rates.