Author

Rafael Calais Gaspar

Yale UniversityORCID 0000-0002-2208-3527Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Ali R. NasiriiD· 1 shared Birgit KnebeliD· 1 shared Daniel F. VatneriD· 1 shared Dean YimlamaiiD· 1 shared Gerald I. ShulmaniD· 1 shared Ikki SakumaiD· 1 shared Jie Zheng· 1 shared Kitt Falk PeterseniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperPathology

Ali R. NasiriORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

PathologyProceedings of the National Academy of SciencesPeer-reviewedMay 1, 2025

✦ In-depth digest

Liver lipid droplet cholesterol content is a key determinant of metabolic dysfunction-associated steatohepatitis

Ikki Sakuma, Rafael Calais Gaspar, Ali R. Nasiri…·Gerald I. Shulman

Cholesterol accumulation in hepatic lipid droplets drives inflammation and fibrosis in mouse and human MASH and is reversed by inhibiting cholesterol synthesis or knocking down Coasy or Hsd17b13.

46 citationstop 1%

mousehuman

𝕏 PostBluesky