Blake Hanson

This study analyzes the pangenome of Proteus mirabilis to reveal lineage-specific antimicrobial resistance profiles and discordant genotype-phenotype correlations across 1,027 genomes.

This study shows that the CRKp lineage CG307 is increasing in UTIs in the Southern US and has traits promoting urinary tract tropism.

The paper characterizes recalcitrant enterococcal bacteremia through clinical and genomic analysis, finding species-specific genetic adaptations in persistent infections.

This study examines TBDR mutations in P. aeruginosa clinical isolates and their association with cefiderocol resistance and heteroresistance.

This study shows that ACL loss in the heart increases glucose oxidation and reduces citrate efflux, leading to metabolic remodeling and cardiac dysfunction.

This study identifies mobile genetic elements driving β-lactamase gene amplification in non-CP-CRE bloodstream infections through genomic analysis.

This study shows that D2-HG induces cachexia in mice by disrupting NAD+ homeostasis and autophagy, revealing metabolic vulnerabilities in skeletal muscle.

This study identifies non-carbapenemase-producing CRE mechanisms in recurrent Enterobacterales infections driven by porin loss and β-lactamase gene amplification.

SVants detects structural variations in bacterial genomes using long-read sequencing, accurately identifying transposon insertion sites and repeat counts in an E. coli reference.