Author

Sirui Li

Center for Excellence in Molecular Cell ScienceORCID 0000-0002-2267-4335Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Anhui Wang· 1 shared Bee Luan KhooiD· 1 shared Bo SuniD· 1 shared Borui Zhu· 1 shared Chenqi XuiD· 1 shared Dinglin ZhangiD· 1 shared Fei ShaoiD· 1 shared Guohui LiiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

Anhui Wang

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Catch-bond engineering surpasses high-affinity maturation for T cell receptor therapies against solid tumors

Tianqi Huang, Runyu Wang, Dinglin Zhang, Siqi Wu, Yuanhao Wang, Yuanhao Wang, Zhengxu Ren, Sifan Wang, Lan Li, Yan Zhou, Xiaojing Wang, Yanling Bao, Mingyu Fan, Luxue Zhang, Junshuang Liu, , Xiang Zhao

This study shows that catch-bond engineering improves TCR-T cell therapy efficacy against solid tumors without off-target toxicity, surpassing traditional high-affinity maturation strategies.

bioRxiv · Jul 29, 2026 · PreprintImmunology

Engineering magnetically guided bacteriophages for precision antimicrobial therapy and targeted biofilm eradication

Yeping Ma, Sylvia Yang Liu, Minqi Hu, Wei Wei, Kaman Ma, Borui Zhu, Sirui Li, Bee Luan Khoo, Song Lin Chua

This paper engineers bacteriophages with iron nanoparticles to enable magnetic guidance, improving their targeting of biofilms and reducing systemic effects in vivo.

bioRxiv · Oct 5, 2025 · PreprintMicrobiology