SRSF3 knockdown-induced cellular senescence as a possible therapeutic strategy for non-small cell lung cancer
Shinji Nakamichi, Natalia von Muhlinen, Leo Yamada, Jilian R. Melamed, Tyler Ellis Papp, Hamideh Parhiz, Drew Weissman, Izumi Horikawa, Curtis C. Harris
This study shows that knocking down SRSF3 induces cellular senescence in NSCLC cells, including those without targetable mutations, suggesting a potential new therapeutic strategy.
Carcinogenesis · Oct 1, 2025Peer-reviewedCancer Biology