Author

Jean-Martin Harder

Friedrich Schiller University JenaORCID 0000-0002-2322-5371Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:metabolism & bioenergetics· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

Ute A. HellmichiD· 2 shared Annika WagneriD· 1 shared Audrey BelotiD· 1 shared Blake CarringtoniD· 1 shared Caiyong CheniD· 1 shared Charlotte GuhliD· 1 shared Eric SchwegleriD· 1 shared Harold Smith· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

Ute A. HellmichORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintAug 3, 2026

A conserved vesicular circuit enables metabolic adaptation and maintains systemic heme homeostasis

Sohini Dutt, Simon Beardsley, Xiaojing Yuan…·Iqbal Hamza

The paper identifies a conserved vesicular circuit that maintains heme homeostasis by rerouting intracellular heme flux, showing its role in metabolic adaptation across species.

DOI 10.64898/2026.07.31.742071

C. eleganszebrafish

𝕏 PostBluesky

BiophysicsbioRxivPreprintJul 23, 2025

Inhibitor fluorination pattern tunes chemically induced protein dimerization

Eric Schwegler, Jean-Martin Harder, Marco D. Preuss…·Ute A. Hellmich

This study shows that fluorination of inhibitors can tune protein dimerization affinity by altering enzyme-inhibitor interactions and dynamics.

1 citation

humanproteomics

𝕏 PostBluesky