Author

Matthew Joseph Schiewer

Thomas Jefferson UniversityORCID 0000-0002-2325-4228Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Ayesha A. ShafiiD· 2 shared Adam SharpiD· 1 shared Charalambos SolomidesiD· 1 shared Christopher M. McNairiD· 1 shared Denisa BogdaniD· 1 shared Drithi Patel· 1 shared Elise G. DeArment· 1 shared Emad S. AlnemriiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Ayesha A. ShafiORCID

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2 papers

Recent·Most cited

Cancer BiologyMolecular OncologyPeer-reviewedSep 7, 2025

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration-resistant prostate cancer

Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada…·Matthew Joseph Schiewer

This study examines how PARP inhibitors affect transcriptional responses in prostate cancer patients of different racial backgrounds, finding race-based differences in PARP1 expression and distinct transcriptional programs for each inhibitor.

DOI 10.1002/1878-0261.70098

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologyOncogenePeer-reviewedSep 12, 2024

AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer

Sumaira Sardar, Christopher M. McNair, Lakshmi Ravindranath…·Ayesha A. Shafi

This study identifies CBP/p300 as critical for DNA repair in prostate cancer and shows that targeting it enhances therapeutic response.

21 citations

humanbulk RNA-seq

𝕏 PostBluesky