Novel biochemical, structural and systems insights into inflammatory signaling revealed by contextual interaction proteomics
Rodolfo Ciuffa, Federico Uliana, Jonathan Mannion, Martin Mehnert, Tencho Tenev, Cathy Marulli, Ari Satanowski, Lena Maria Leone Keller, Pilar Natalia Rodilla-Ramírez, Alessandro Ori, Matthias Gstaiger, Pascal Meier, Ruedi H. Aebersold
The paper presents an integrated experimental and computational strategy to model protein-protein interactions in cellular context, applied to the TNF-receptor signaling complex.
Proceedings of the National Academy of Sciences · Sep 30, 2022Peer-reviewedSystems Biology