Carlos Pascual-Caro

This study shows that reducing Letm1 increases mitochondrial Ca2+ retention, overactivates metabolism, and enhances long-term memory in flies and mice.

This paper introduces a method to capture and quantify activity-driven trafficking of endogenous synaptic proteins using proximity labeling, revealing new insights into synaptic translocation dynamics.

The paper identifies TZAP as a developmental regulator of mitochondrial homeostasis critical for activity-dependent synaptic connectivity in Drosophila.

This study shows that neuronal activity drives the translocation of LGI1 and ADAM23 to the synaptic cleft, adjusting excitatory neurotransmission based on activity history.