Author

Panu Jaakkola

Turku University HospitalORCID 0000-0002-2365-4985Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:spatial transcriptomics· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Olli KallioniemiiD· 2 shared Petrus JärvineniD· 2 shared Teijo S. PellineniD· 2 shared Tuomas K. MirttiiD· 2 shared Annabrita HemmesiD· 1 shared Antti HassineniD· 1 shared Antti Sakari RannikkoiD· 1 shared Elisa KankkuneniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCancer Biology

Olli KallioniemiORCID

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2 papers

Recent·Most cited

Pathway-centric multi-omics and functional precision medicine reveal shared drug vulnerabilities in heterogeneous adult Wilms tumor

Minttu Polso, Romika Kumari, Tamara J. Luck, Piia Mikkonen, Katja Välimäki, Ruusu‐Maaria Merivirta, Minna Malmstedt, Johanna Lehtonen, Erika Romppanen, Sara Kuusela, Antti Hassinen, Janna Saarela, Teijo S. Pellinen, Panu Jaakkola, Pia Suonpää, , Vilja M. Pietiäinen

This study identifies shared drug vulnerabilities in adult Wilms tumor through multi-omics and functional assays, showing pathway-level dependencies predict drug responses better than single-gene biomarkers.

bioRxiv · Jun 25, 2026 · PreprintCancer Biology

Fibroblast Activation Protein Defines an Aggressive, Immunosuppressive EMT-associated Tumor Subtype in Highly Inflamed Localized Clear Cell Renal Cell Carcinoma

Teijo S. Pellinen, Lassi Luomala, Kalle Mattila, Annabrita Hemmes, Katja E. Välimäki, Oscar E. Brück, Lassi Paavolainen, Elisa Kankkunen, Harry Nísen, Petrus Järvinen, Leticia Castillon, Sakari Vanharanta, Paula Vainio, Olli Kallioniemi, Panu Jaakkola, Tuomas K. Mirtti

The paper identifies FAP-expressing EMT-associated cancer cells in highly inflamed localized ccRCC as an aggressive, immunosuppressive subtype linked to poor prognosis and metastasis.

bioRxiv · Oct 27, 2024 · PreprintCancer Biology