Author

Laura Mahoney‐Sanchez

The Francis Crick InstituteORCID 0000-0002-2377-8267Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:differential expression· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

James R. EvansiD· 2 shared Karishma D’SaiD· 2 shared Patricia Lopez-GarciaiD· 2 shared Sonia GandhiiD· 2 shared Stephanie StrohbueckeriD· 2 shared Aaron Z. WageniD· 1 shared Alex GriffithsiD· 1 shared Alexis PenverneiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersNeuroscience

James R. EvansORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 13, 2025

The SNCA A53T mutation sensitizes human neurons and microglia to ferroptosis

Laura Mahoney‐Sanchez, Hannah J Lucas-Clarke, Alexis Penverne…·Sonia Gandhi

This study shows that the SNCA A53T mutation increases vulnerability to ferroptosis in neurons and microglia, suggesting 15-LO inhibition as a potential therapeutic target for Parkinson's disease.

1 citation

humanproteomics

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NeurosciencebioRxivPreprintFeb 28, 2024

GLP-1 receptor agonism ameliorates Parkinsons disease through modulation of neuronal insulin signalling and glial suppression

Dilan S. Athauda, James R Evans, Laura Mahoney‐Sanchez…·Sonia Gandhi

This study shows GLP-1R agonism improves Parkinson's disease by restoring neuronal insulin signaling and reducing glial inflammation, with clinical benefits in patients with higher baseline MAPK expression.

7 citations

humanexperimental assay

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