Xiong Xiao

Incorporation of single-neuron projectome-based connectivity motifs enhances the cortex-specific performance of artificial neural networks

This paper develops a connectome-informed neural network algorithm that improves RNN and LLM performance by incorporating natural cortical connectivity motifs.

Modular organization and selective motifs in the insula provide structural priors for efficient learning

The paper maps the insular cortex's intra-architecture and shows it provides computational advantages for efficient learning in neural networks.

Dynorphin modulates motivation through a pallido-amygdala cholinergic circuit

This study shows dynorphin modulates motivation via a pallido-amygdala cholinergic circuit by both disinhibiting and autoinhibiting cholinergic transmission in mice.

Cell-type-specific striatal modulation of amygdalar acetylcholine in salience assignment

The paper shows striatal D1 and D2 MSNs regulate BLA ACh levels, influencing salience assignment through distinct mechanisms.

Opposing contributions of GABAergic and glutamatergic ventral pallidal neurons to motivational behaviours

This study shows that GABAergic and glutamatergic ventral pallidal neurons control opposing motivational behaviors in mice by encoding positive and negative motivational value.