Phong Thanh Tran

The paper determines the cryo-EM structure of the holocentric CCAN from Bombyx mori, revealing a self-contained dimer that forms a point-centromere-like architecture and incorporates novel Centromeric Subunit proteins.

This study creates kinesin-6 and kinesin-14 chimeras in fission yeast to show that domain functions dictate motor localization, directionality, and force production, leading to aneuploidy.

The paper identifies PP6 phosphatase and Elongator as regulators of kinesin 5-dependent spindle assembly by controlling microtubule regulator levels in fission yeast.