Author

Bert L. Semler

University of California, IrvineORCID 0000-0002-2424-5155Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Alexander Nathaniel GarciaiD· 1 shared Alexis BouiniD· 1 shared Ambrocio SancheziD· 1 shared Dana DuongiD· 1 shared Dheva SetiaputraiD· 1 shared Elodie BourniqueiD· 1 shared Gisselle SantiagoiD· 1 shared Junyi LiiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Alexander Nathaniel GarciaORCID

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1 paper

Recent·Most cited

MicrobiologyNature CommunicationsPeer-reviewedApr 5, 2025

Cooperative Role of PACT and ADAR1 in Preventing Aberrant PKR Activation by Self-Derived Double-Stranded RNA

Lavanya Manjunath, Gisselle Santiago, Pedro Ortega…·Rémi Buisson

The paper identifies PACT as a key inhibitor of PKR during viral infection and shows that PACT and ADAR1 cooperate to prevent aberrant PKR activation by self-dsRNAs.

24 citationstop 2%

humanexperimental assay

𝕏 PostBluesky