Author

Alexis Bouin

University of California, IrvineORCID 0009-0008-6712-9163Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Organism:mouse· 1

Frequent Co-Authors

Alejandro Amando Guzman· 1 shared Alexander Nathaniel GarciaiD· 1 shared Ambrocio SancheziD· 1 shared Anh Phuong Luu· 1 shared Bert L. SemleriD· 1 shared Dana DuongiD· 1 shared Dheva SetiaputraiD· 1 shared Elodie BourniqueiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMicrobiology

Alejandro Amando Guzman

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintJun 27, 2025

Differences between human and rodent nitric oxide production dictate susceptibility to tick-borne Rickettsia.

Anh Phuong Luu, Alejandro Amando Guzman, Alexis Bouin…·Thomas Burke

The paper identifies differences in nitric oxide production between human and rodent macrophages as a key factor in susceptibility to tick-borne Rickettsia.

3 citations

mousehuman

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MicrobiologyNature CommunicationsPeer-reviewedApr 5, 2025

Cooperative Role of PACT and ADAR1 in Preventing Aberrant PKR Activation by Self-Derived Double-Stranded RNA

Lavanya Manjunath, Gisselle Santiago, Pedro Ortega…·Rémi Buisson

The paper identifies PACT as a key inhibitor of PKR during viral infection and shows that PACT and ADAR1 cooperate to prevent aberrant PKR activation by self-dsRNAs.

24 citationstop 2%

humanexperimental assay

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