Author
University of California, IrvineORCID 0000-0003-4216-3695Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Kevin Cao, Dat P. Ha, Jesse Hulahan…·Thomas Farid Martinez
The paper identifies NISM, a microprotein encoded by HDAC5, which regulates nucleolar formation and rRNA synthesis by modulating DHX9 activity and phase separation.
Pedro Ortega, Elodie Bournique, Junyi Li…·Rémi Buisson
This study identifies APOBEC3B as the enzyme responsible for ssDNA breakage during replication catastrophe induced by ATR inhibition, revealing a mechanism for PARP1 trapping and synthetic lethality with PARP inhibitors.
Lavanya Manjunath, Gisselle Santiago, Pedro Ortega…·Rémi Buisson
The paper identifies PACT as a key inhibitor of PKR during viral infection and shows that PACT and ADAR1 cooperate to prevent aberrant PKR activation by self-dsRNAs.