The bacterial ESCRT-III PspA rods thin lipid tubules and increase membrane curvature through helix α0 interactions
Esther Hudina, Stephan Schott‐Verdugo, Benedikt Junglas, Mirka Kutzner, Ilona Ritter, Nadja Hellmann, Dirk Schneider, Holger Gohlke, Carsten Sachse
This study shows how PspA rods thin lipid tubules by inducing membrane curvature through N-terminal helix 0 interactions, overcoming bending energy via molecular mechanisms.
Proceedings of the National Academy of Sciences · Aug 4, 2025Peer-reviewedBiophysics